Why Muscle Glycogen can’t be Used directly for Energy Utilization for other cells?

In Muscle - Muscles lack Glucose 6 Phosphatase •Phosphoglucomutase catalyzes the isomerization of glucose-1-phosphate to glucose-6- phosphate. •Glucose-6-Phosphate gets directly utilized in Glycolysis

In Liver - Liver has Glucose 6 Phosphatase

  • Phosphoglucomutase catalyzes the isomerization of glucose-1-phosphate to glucose-6-phosphate.
  • Glucose-6-phosphatase hydrolyzes glucose-6-phosphate to produce free glucose.
  • Free glucose released into the bloodstream for energy supply or maintaining blood glucose levels.
  • Muscle lacks Glucose 6 Phosphatase.
  • G-6-P produced by muscle glycogen can’t Cross its cell membrane.
  • Thus it will be used by muscle cell itself.
  • Therefore muscle glycogen can’t provide energy to other cells