Why Muscle Glycogen can’t be Used directly for Energy Utilization for other cells?
In Muscle - Muscles lack Glucose 6 Phosphatase •Phosphoglucomutase catalyzes the isomerization of glucose-1-phosphate to glucose-6- phosphate. •Glucose-6-Phosphate gets directly utilized in Glycolysis
In Liver - Liver has Glucose 6 Phosphatase
- Phosphoglucomutase catalyzes the isomerization of glucose-1-phosphate to glucose-6-phosphate.
- Glucose-6-phosphatase hydrolyzes glucose-6-phosphate to produce free glucose.
- Free glucose released into the bloodstream for energy supply or maintaining blood glucose levels.
- Muscle lacks Glucose 6 Phosphatase.
- G-6-P produced by muscle glycogen can’t Cross its cell membrane.
- Thus it will be used by muscle cell itself.
- Therefore muscle glycogen can’t provide energy to other cells