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Heparin is known as a “clearing factor”

• because it activates lipoprotein lipase (LPL), an enzyme responsible for breaking down triglycerides in lipoproteins like chylomicrons and very low-density lipoproteins (VLDL).
• This action helps in the rapid clearance of lipid-rich particles from the blood, making plasma appear clear instead of turbid.
• By promoting lipid metabolism, heparin reduces circulating triglyceride levels.
• useful in studying lipid metabolism and managing hyperlipidemia.