HDL is involved in “Reverse Cholesterol Transport”

• HDL is the main transport form of cholesterol from peripheral tissue to liver, which is later excreted through bile .This is called reverse cholesterol transport by HDL.
• Excretion of cholesterol needs prior esterification with PUFA. Thus PUFA will help in lowering of cholesterol in the body,and so PUFA is anti-atherogenic
• The level of HDL in serum is inversely related to the incidence of myocardial infarction. As it is “anti-atherogenic” or protective in nature, HDL is known as “good cholesterol in common parlance”