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 ====Example List of questions for PG (MD Biochemistry Students)==== ====Example List of questions for PG (MD Biochemistry Students)====
 =====Core biochemistry===== =====Core biochemistry=====
-  - How H2O2 is formed in human body | Describe biochemical reactions causing H2O2 mediated damage to cell membrane lipid| How NADPH is used to metabolize H2O2| How G6PD mutations are inherited| What are biochemical events causing hemolysis in G6PD deficiency| Explain principle of Methelene Blue based screening test for diagnosis of G6PD deficiency +  - [[How H2O2 is formed in human body | Describe biochemical reactions causing H2O2 mediated damage to cell membrane lipid| How NADPH is used to metabolize H2O2| How G6PD mutations are inherited| What are biochemical events causing hemolysis in G6PD deficiency| Explain principle of Methelene Blue based screening test for diagnosis of G6PD deficiency]] 
-  - Explain role of Fe2+, heme and globins in hemoglobin mediated O2 and CO2 transport. Emphasize role of distal and proximal histidine of globin. Enlist series of molecular events responsible for increased O2 affinity of Hb when one of its globin bind O2. Explain molecular basis of relationship between O2 and carbon monoxide in context of hemoglobin structure and function. What is carbon monoxide concentration in various environment +  - [[Explain role of Fe2+, heme and globins in hemoglobin mediated O2 and CO2 transport. Emphasize role of distal and proximal histidine of globin. Enlist series of molecular events responsible for increased O2 affinity of Hb when one of its globin bind O2. Explain molecular basis of relationship between O2 and carbon monoxide in context of hemoglobin structure and function. What is carbon monoxide concentration in various environment]] 
-  - Describe biochemical structure of bacterial cell wall and give overview of its synthesis. How does it differ in Gram positive and negative organisms. Describe biochemical mechanism of action of antibiotics affecting bacterial cell wall. Explain biochemical strategies used by bacteria to develop resistance to these antibiotics.      +  - [[Describe biochemical structure of bacterial cell wall and give overview of its synthesis. How does it differ in Gram positive and negative organisms. Describe biochemical mechanism of action of antibiotics affecting bacterial cell wall. Explain biochemical strategies used by bacteria to develop resistance to these antibiotics.]]      
-  - Explain mechanism of autoimmune disease following bacterial infection and immune-mediated hypersensitivity to antibiotics+  - [[Explain mechanism of autoimmune disease following bacterial infection and immune-mediated hypersensitivity to antibiotics]]
   - [[Protein life cycle]]   - [[Protein life cycle]]
-  - Protein sequencing using Edman reaction +  - [[Protein sequencing using Edman reaction]] 
-  - Protein folding and its perturbation causing diseases +  - [[Protein folding and its perturbation causing diseases]] 
-  - Post-translational modifications in collagen+  - [[Post-translational modifications in collagen]]
   - [[Enzymatic pathways of methemoglobin reduction and biochemical basis for use of methelene blue in treatment of methemoglobinemia.]]   - [[Enzymatic pathways of methemoglobin reduction and biochemical basis for use of methelene blue in treatment of methemoglobinemia.]]
   - [[Enzymatic pathways of methemoglobin reduction and biochemical basis for use of methelene blue in reagents for diagnosis of G6PD deficiency.]]   - [[Enzymatic pathways of methemoglobin reduction and biochemical basis for use of methelene blue in reagents for diagnosis of G6PD deficiency.]]
   - [[Amino acid substitutions in hemoglobin variants and correlation with electrophoretic mobility and sickling test]]   - [[Amino acid substitutions in hemoglobin variants and correlation with electrophoretic mobility and sickling test]]
-  - Single molecule enzymology +  - [[Single molecule enzymology]] 
-  - Molar absorptivity of NADH and calculation of enzyme factors +  - [[Molar absorptivity of NADH and calculation of enzyme factors]] 
-  - Recombinant fusion proteins in affinity chromatography purification of proteins +  - [[Recombinant fusion proteins in affinity chromatography purification of proteins]] 
-  - artifacts from RNA world +  - [[artifacts from RNA world]] 
-  - Enzymes do not affect equilibrium of chemical reaction. +  - [[Enzymes do not affect equilibrium of chemical reaction.]] 
-  - Km and Vmax in competitive and noncompetitive enzyme inhibition +  - [[Km and Vmax in competitive and noncompetitive enzyme inhibition]] 
-  - Catalytic constant and catalytic efficiency +  - [[Catalytic constant and catalytic efficiency]] 
-  - Difference between feedback regulation and feedback inhibition +  - [[Difference between feedback regulation and feedback inhibition]] 
-  - Compare and contrast five Basic Local Alignment Search Tools (BLAST) +  - [[Compare and contrast five Basic Local Alignment Search Tools (BLAST)]] 
-  - Cytochrome P-450 +  - [[Cytochrome P-450]] 
-  - Cyanide poisoning – biochemical consequences and biochemical basis of its treatment +  - [[Cyanide poisoning – biochemical consequences and biochemical basis of its treatment]] 
-  - States of respiratory control +  - [[States of respiratory control]] 
-  - Uncouplers of respiratory chain +  - [[Uncouplers of respiratory chain]] 
-  - Thermogenesis in brown adipose tissue +  - [[Thermogenesis in brown adipose tissue]] 
-  - Overview of carbohydrate metabolism +  - [[Overview of carbohydrate metabolism]] 
-  - Overview of fatty acid metabolism +  - [[Overview of fatty acid metabolism]] 
-  - Overview of cholesterol metabolism +  - [[Overview of cholesterol metabolism]] 
-  - Overview of amino acid metabolism +  - [[Overview of amino acid metabolism]] 
-  - Overview of transport of lipids in blood +  - [[Overview of transport of lipids in blood]] 
-  - HDL/VLDL/LDL/Chylomicron +  - [[HDL/VLDL/LDL/Chylomicron]] 
-  - Metabolic interrelationship among adipose tissue, liver and extrahepatic tissue +  - [[Metabolic interrelationship among adipose tissue, liver and extrahepatic tissue]] 
-  - Interconversion among glucose, TG and amino acids +  - [[Interconversion among glucose, TG and amino acids]] 
-  - Reactions unique to gluconeogenesis +  - [[Reactions unique to gluconeogenesis]] 
-  - Metabolism of propipnate +  - [[Metabolism of propipnate]] 
-  - Control of glycolysis and gluconeogenesis by Fructose 2-6 biphosphate +  - [[Control of glycolysis and gluconeogenesis by Fructose 2-6 biphosphate]] 
-  - Major Glucose transporters +  - [[Major Glucose transporters]] 
-  - Screening and diagnosis of gestational diabetes mellitus +  - [[Screening and diagnosis of gestational diabetes mellitus]] 
-  - Regulation of ketogenesis +  - [[Regulation of ketogenesis]] 
-  - Biochemical events leading to of ketoacidosis in diabetes mellitus +  - [[Biochemical events leading to of ketoacidosis in diabetes mellitus]] 
-  - Regulation of acetyl Co-A carboxylase. +  - [[Regulation of acetyl Co-A carboxylase.]] 
-  - Regulation of Carnitine palmitoyl transferase 1 (CPT 1) by insulin +  - [[Regulation of Carnitine palmitoyl transferase 1 (CPT 1) by insulin]] 
-  - Mechanism of action of aspirin as anti-platelet-aggregation agent. +  - [[Mechanism of action of aspirin as anti-platelet-aggregation agent.]] 
-  - Mechanism of action of corticosteroid as anti-inflammatory agent +  - [[Mechanism of action of corticosteroid as anti-inflammatory agent]] 
-  - Aspirin vs. corticosteroid as drugs acting on eicosanoid synthetic pathway +  - [[Aspirin vs. corticosteroid as drugs acting on eicosanoid synthetic pathway]] 
-  - Three groups of eicosanoids and their biosynthetic origin +  - [[Three groups of eicosanoids and their biosynthetic origin]] 
-  - EPA and DHA – biochemical basis of their role in health +  - [[EPA and DHA – biochemical basis of their role in health]] 
-  - HDL/VLDL/Chylomicron metabolism +  - [[HDL/VLDL/Chylomicron metabolism]] 
-  - Triacylglycerol metabolism and its regulation in adipose tissue +  - [[Triacylglycerol metabolism and its regulation in adipose tissue]] 
-  - Perilipin and adipose tissue lipid droplets +  - [[Perilipin and adipose tissue lipid droplets]] 
-  - Hormones and adipose tissue +  - [[Hormones and adipose tissue]] 
-  - Biochemical events in adipose tissue after a meal +  - [[Biochemical events in adipose tissue after a meal]] 
-  - Biochemical events in adipose tissue in fasting +  - [[Biochemical events in adipose tissue in fasting]] 
-  - Molecular basis for regulation of cholesterol biosynthesis in a cell +  - [[Molecular basis for regulation of cholesterol biosynthesis in a cell]] 
-  - Molecular basis for regulation of HMG Co-A reductase in a cell +  - [[Molecular basis for regulation of HMG Co-A reductase in a cell]] 
-  - Functions of non-cholesterol product of cholesterol synthetic patway +  - [[Functions of non-cholesterol product of cholesterol synthetic pathway]] 
-  - Factors affecting cholesterol balance at cellular level +  - [[Factors affecting cholesterol balance at cellular level]] 
-  - Transport of cholesterol among tissues in humans +  - [[Transport of cholesterol among tissues in humans]] 
-  - Structure, genetics and biomedical importance of Lp(a) +  - [[Structure, genetics and biomedical importance of Lp(a)]] 
-  - Inherited disorders of plasma lipoproteins +  - [[Inherited disorders of plasma lipoproteins]] 
-  - Biochemical basis of etiology, clinical features, diagnosis and treatment of various hyperphenylalaninemia +  - [[Biochemical basis of etiology, clinical features, diagnosis and treatment of various hyperphenylalaninemia]] 
-  - Non-protein nitrogen products of tyrosine and tryptophan and various drugs affecting their metabolism +  - [[Non-protein nitrogen products of tyrosine and tryptophan and various drugs affecting their metabolism]] 
-  - Maple syrup urine diseases +  - [[Maple syrup urine diseases]] 
-  - Biosynthesis and metabolism of serotonin and metatonin +  - [[Biosynthesis and metabolism of serotonin and metatonin]] 
-  - Biochemical basis of etiology, clinical features, diagnosis and treatment of various hyperhomocystinemia +  - [[Biochemical basis of etiology, clinical features, diagnosis and treatment of various hyperhomocystinemia]] 
-  - Biochemical basis of etiology, clinical features, diagnosis and treatment of various disorders of lipid malabsorption +  - [[Biochemical basis of etiology, clinical features, diagnosis and treatment of various disorders of lipid malabsorptio]] 
-  - Biochemical cause of major signs and symptoms of porphyrias +  - [[Biochemical cause of major signs and symptoms of porphyrias]] 
-  - Biochemical basis of etiology, clinical features, diagnosis and treatment of unconjugated neonatal hyperbilirubinemia. +  - [[Biochemical basis of etiology, clinical features, diagnosis and treatment of unconjugated neonatal hyperbilirubinemia.]] 
-  - DNA packaging in metaphase chromosomes +  - [[DNA packaging in metaphase chromosomes]] 
-  - Possible roles of modified histones +  - [[Possible roles of modified histones]] 
-  - Major features of human mitochondrial DNA +  - [[Major features of human mitochondrial DNA]] 
-  - Viral integration and transposons in human genome +  - [[Viral integration and transposons in human genome]] 
-  - Structure, function and inhibitors of DNA topoisomerases +  - [[Structure, function and inhibitors of DNA topoisomerases]] 
-  - DNA damage – causes, types, repair pathways and repair fedality +  - [[DNA damage – causes, types, repair pathways and repair fedality]] 
-  - Double stranded break repair mechanisms +  - [[Double stranded break repair mechanisms]] 
-  - Transcription cycle +  - [[Transcription cycle]] 
-  - Transcription control regions for eukaryotic genes +  - [[Transcription control regions for eukaryotic genes]] 
-  - Post-trancriptional modification of primary transcript +  - [[Post-trancriptional modification of primary transcript]] 
-  - Mechanism of intron removal and alternative splicing +  - [[Mechanism of intron removal and alternative splicing]] 
-  - Alternative promotor utilization +  - [[Alternative promotor utilization]] 
-  - Biogenesis and function of miRNA +  - [[Biogenesis and function of miRNA]] 
-  - Degeneracy of genetic code, concept and mechanism of wobbling phenomenon +  - [[Degeneracy of genetic code, concept and mechanism of wobbling phenomenon]] 
-  - Properties of genetic code +  - [[Properties of genetic code]] 
-  - Point mutations and frame shift mutations +  - [[Point mutations and frame shift mutations]] 
-  - Circularization of mRNA during translation +  - [[Circularization of mRNA during translation]] 
-  - Role of methyl-GTP cap and poly-A tail in translation +  - [[Role of methyl-GTP cap and poly-A tail in translation]] 
-  - Antibiotics inhibiting protein synthesis +  - [[Antibiotics inhibiting protein synthesis]] 
-  - cis and trans epigenetic signals +  - [[cis and trans epigenetic signals]] 
-  - Propagation of epigenetic signal after DNA replication +  - [[Propagation of epigenetic signal after DNA replication]] 
-  - Properties of enhancers +  - [[Properties of enhancers]] 
-  - DNA motifs +  - [[DNA motifs]] 
-  - Various ways of gene regulation +  - [[Various ways of gene regulation]] 
-  - Regulation of mRNA stability +  - [[Regulation of mRNA stability]] 
-  - Restriction - Enzymes used in recombinant DNA research +  - [[Restriction - Enzymes used in recombinant DNA research]] 
-  - structure pf plasmid pBR322 and its use in recombinant DNA technology +  - [[structure pf plasmid pBR322 and its use in recombinant DNA technology]] 
-  - genomic and cDNA library +  - [[genomic and cDNA library]] 
-  - DNA sequencing by Sanger'+  - [[DNA sequencing by Sanger's]] 
-  - Transgenic animals and knockout animals +  - [[Transgenic animals and knockout animals]] 
-  - Membrane asymmetry +  - [[Membrane asymmetry]] 
-  - specialized plasma membranes +  - [[specialized plasma membranes]] 
-  - Structure of K+ channel and selectivity +  - [[Structure of K+ channel and selectivity]] 
-  - Structure and function of clathrin coated vesicles +  - [[Structure and function of clathrin coated vesicles]] 
-  - Group 1 and group 2 hormones +  - [[Group 1 and group 2 hormones]] 
-  - Biosynthesis, molecular mechanism and disorders of calcitriol. +  - [[Biosynthesis, molecular mechanism and disorders of calcitriol.]] 
-  - Iodide metabolism in thyroid follicles +  - [[Iodide metabolism in thyroid follicles]] 
-  - Regulation of gene expression by class 1 hormones +  - [[Regulation of gene expression by class 1 hormones]] 
-  - G protein coupled receptors +  - [[G protein coupled receptors]] 
-  - Phospholipase C mediated second messenger system +  - [[Phospholipase C mediated second messenger system]] 
-  - Insulin signaling - +  - [[Insulin signaling -]] 
-  - Nuclear receptor superfamily +  - [[Nuclear receptor superfamily]] 
-  - Absorption of iron +  - [[Absorption of iron]] 
-  - Biochemical functions of various types of vitamin A and provitamin A +  - [[Biochemical functions of various types of vitamin A and provitamin A]] 
-  - Vitamin K cycle and drugs acting on it +  - [[Vitamin K cycle and drugs acting on it]] 
-  - Mechanism of methotrexate and 5-flurouracil +  - [[Mechanism of methotrexate and 5-flurouracil]] 
-  - Mechanism of carboxylation by biotin +  - [[Mechanism of carboxylation by biotin]] 
-  - Sources of free radicals and tissue damages caused by them +  - [[Sources of free radicals and tissue damages caused by them]] 
-  - Antioxidents can be pro-oxidents +  - [[Antioxidents can be pro-oxidents]] 
-  - Cotranslational targeting of secretory proteins to endoplasmic reticulum +  - [[Cotranslational targeting of secretory proteins to endoplasmic reticulum]] 
-  - Peroxismal protein sorting and Zellweger syndrome +  - [[Peroxismal protein sorting and Zellweger syndrome]] 
-  - Entry of protein from cytoplasm to nucleoplasm +  - [[Entry of protein from cytoplasm to nucleoplasm]] 
-  - Entry of protein from cytoplasm to mitochondia +  - [[Entry of protein from cytoplasm to mitochondia]] 
-  - Cotranslational insertion of membrane proteins +  - [[Cotranslational insertion of membrane proteins]] 
-  - Chaperones +  - [[Chaperones]] 
-  - Ubiquitin mediated protein degradation +  - [[Ubiquitin mediated protein degradation]] 
-  - COP 1, COP2 and clathrin coated vesicles +  - [[COP 1, COP2 and clathrin coated vesicles]] 
-  - Lectins +  - [[Lectins]] 
-  - Role of dolichol in synthesis of N-linked glycoprotein +  - [[Role of dolichol in synthesis of N-linked glycoprotein]] 
-  - GPI anchored proteind +  - [[GPI anchored proteind]] 
-  - Formation and consequences of advanced glycation endproducts +  - [[Formation and consequences of advanced glycation endproducts]] 
-  - Biochemical basis of difference in clinical presentation of seasonal flu and bird flu/swine flu +  - [[Biochemical basis of difference in clinical presentation of seasonal flu and bird flu/swine flu]] 
-  - Order and location of various post-translational processing of collagen +  - [[Order and location of various post-translational processing of collagen]] 
-  - Biochemical mechanism of bone resorption in ostoclast +  - [[Biochemical mechanism of bone resorption in ostoclast]] 
-  - Molecular organization in cartilages +  - [[Molecular organization in cartilages]] 
-  - Biochemical events occurring during skeletal muscle contraction +  - [[Biochemical events occurring during skeletal muscle contraction]] 
-  - Biochemical peculiarities and functions of sarcoplasmic reticulum +  - [[Biochemical peculiarities and functions of sarcoplasmic reticulum]] 
-  - Dystrophin and musle cytoskeleton +  - [[Dystrophin and musle cytoskeleton]] 
-  - Regulation of smooth muscle contraction +  - [[Regulation of smooth muscle contraction]] 
-  - Difference in biochemical mechanism between skeletal and smooth muscle contraction +  - [[Difference in biochemical mechanism between skeletal and smooth muscle contraction]] 
-  - Metabolism and function of nitrogen oxide +  - [[Metabolism and function of nitrogen oxide]] 
-  - Biochemical difference between muscle fibers and fuel used by sprinter and marathon runner +  - [[Biochemical difference between muscle fibers and fuel used by sprinter and marathon runner]] 
-  - Non-heme transport of iron in enterocytes +  - [[Non-heme transport of iron in enterocytes]] 
-  - Transferrin cycle +  - [[Transferrin cycle]] 
-  - Regulation of synthesis of Ferritin and Transferrin-receptor +  - [[Regulation of synthesis of Ferritin and Transferrin-receptor]] 
-  - Role of hepcidin in iron metabolism +  - [[Role of hepcidin in iron metabolism]] 
-  - Changes in various laboratory tests in iron deficiency anemia +  - [[Changes in various laboratory tests in iron deficiency anemia]] 
-  - alpha-1 antitrypsin function and deficiency +  - [[alpha-1 antitrypsin function and deficiency]] 
-  - genetics of ABO blood groups +  - [[genetics of ABO blood groups]] 
-  - Metabolism of RBC +  - [[Metabolism of RBC]] 
-  - Important reactions related to oxidative stress in various cells +  - [[Important reactions related to oxidative stress in various cells]] 
-  - RBC cytoskeleton and hereditary spherocytosis +  - [[RBC cytoskeleton and hereditary spherocytosis]] 
-  - Respiratory burst in neutrophils and related disorders +  - [[Respiratory burst in neutrophils and related disorders]] 
-  - Role of NADPH oxidase and myeloperoxidase in neutrophils +  - [[Role of NADPH oxidase and myeloperoxidase in neutrophils]] 
-  - Properties of cytochrome P450 +  - [[Properties of cytochrome P450]] 
-  - Various types of type-2 reactions in metabolism of xenobiotics +  - [[Various types of type-2 reactions in metabolism of xenobiotics]] 
-  - Xenobiotic mediated cell inury +  - [[Xenobiotic mediated cell inury]] 
-  - Mitochondrial theory of aging +  - [[Mitochondrial theory of aging]] 
-  - Role of protein glycation in protein-protein crosslinking +  - [[Role of protein glycation in protein-protein crosslinking]] 
-  - Metabolic theory of aging +  - [[Metabolic theory of aging]] 
-  - Telomere – structure, function and its replication +  - [[Telomere – structure, function and its replication]] 
-  - Ames test for detection of carcinogens +  - [[Ames test for detection of carcinogens]] 
-  - Oncogenes +  - [[Oncogenes]] 
-  - Biochemical basis of apoptosis +  - [[Biochemical basis of apoptosis]] 
-  - Biochemical aspects of metastasis +  - [[Biochemical aspects of metastasis]] 
-  - Mechanism of action of various anticancer drugs +  - [[Mechanism of action of various anticancer drugs]] 
-  - Hypoxia induced molecular events leading to altered gene expression +  - [[Hypoxia induced molecular events leading to altered gene expression]] 
-  - Explain leuminescence, chemileuminescence, bioleuminesence, enhanced chemileuminesence, and electrochemileuminesence +  - [[Explain leuminescence, chemileuminescence, bioleuminesence, enhanced chemileuminesence, and electrochemileuminesence]] 
-  - Dietary reference intake +  - [[Dietary reference intake]] 
-  - Shotgun sequencing +  - [[Shotgun sequencing]] 
-  - Ethics in medical laboratory +  - [[Ethics in medical laboratory]] 
-  - Principle of electrochemileuminesence +  - [[Principle of electrochemileuminesence]] 
-  - Cost minimization, cost-benifit, cost-effectiveness and cost-utility analysis for laboratory tests +  - [[Cost minimization, cost-benifit, cost-effectiveness and cost-utility analysis for laboratory tests]] 
-  - Various types of blood collection tubes for serum separation +  - [[Various types of blood collection tubes for serum separation]] 
-  - Lactic acidosis – causes and biochemical basis of expected results of various laboratory examination +  - [[Lactic acidosis – causes and biochemical basis of expected results of various laboratory examination]] 
-  - Causes and biochemical basis of expected results of various laboratory examination in diabetic ketoacidosis +  - [[Causes and biochemical basis of expected results of various laboratory examination in diabetic ketoacidosis]] 
-  - Biochemical basis of expected results of Blood gas analysis in severe emphysema +  - [[Biochemical basis of expected results of Blood gas analysis in severe emphysema]] 
-  - Biochemical basis of expected results of various laboratory examination in renal tubular acidosis +  - [[Biochemical basis of expected results of various laboratory examination in renal tubular acidosis]] 
-  - Capillary blood sampling – methods and uses +  - [[Capillary blood sampling – methods and uses]] 
-  - Types questions clinicians try to answer by requesting laboratory examinations +  - [[Types questions clinicians try to answer by requesting laboratory examinations]] 
-  - Voltametry in clinical chemistry +  - [[Voltametry in clinical chemistry]] 
-  - Types of bilirubin in plasma and its detection by various methods +  - [[Types of bilirubin in plasma and its detection by various methods]] 
-  - Limitations of use of SI units in clinical chemistry +  - [[Limitations of use of SI units in clinical chemistry]] 
-  - Blunt end recombination of DNA +  - [[Blunt end recombination of DNA]] 
-  - SARS CoV2 lifecycle +  - [[SARS CoV2 lifecycle]] 
-  - Mechanism of action of Vaccines against COVID19 +  - [[Mechanism of action of Vaccines against COVID19]] 
-  - Mechanism of action of Drugs against COVID19 +  - [[Mechanism of action of Drugs against COVID19]] 
-  - Role of Clinical Biochemistry in COVID19 pandemic +  - [[Role of Clinical Biochemistry in COVID19 pandemic]] 
-  - Inflammatory Markers in COVID19 management +  - [[Inflammatory Markers in COVID19 management]] 
-  - Biochemical Differences between delta and omicron variants of SARSCoV2 ant its clinical significance+  - [[Biochemical Differences between delta and omicron variants of SARSCoV2 ant its clinical significance]]
  
 =====Laboratory Medicine===== =====Laboratory Medicine=====
-  - ISO 15189-2012 +  - [[ISO 15189-2012]] 
-  - ISO 15189-2012 vs 2007 +  - [[ISO 15189-2012 vs 2007]] 
-  - NABL-112 +  - [[NABL-112]] 
-  - Process of NABL accreditation +  - [[Process of NABL accreditation]] 
-  - Explain any 10 special terms and definitions used in ISO 15189-2012 +  - [[Explain any 10 special terms and definitions used in ISO 15189-2012]] 
-  - Document control in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Document control in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Identification, control, correction and prevention of nonconformity [in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Identification, control, correction and prevention of nonconformity [in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Internal audit in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Internal audit in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Risk management in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Risk management in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Quality indicators in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Quality indicators in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Personnel records in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Personnel records in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Equipment records in NABL accredited clinical laboratory / requirements in ISO 15189-2012 +  - [[Equipment records in NABL accredited clinical laboratory / requirements in ISO 15189-2012]] 
-  - Reagents and consumables requirements in ISO 15189-2012 / management in NABL accredited clinical laboratory +  - [[Reagents and consumables requirements in ISO 15189-2012 / management in NABL accredited clinical laboratory]] 
-  - Requirements in ISO 15189-2012 about Information for patients and users +  - [[Requirements in ISO 15189-2012 about Information for patients and users]] 
-  - Requirements in ISO 15189-2012 about Request form information +  - [[Requirements in ISO 15189-2012 about Request form information]] 
-  - Requirements in ISO 15189-2012 about verification and validation of examination procedure +  - [[Requirements in ISO 15189-2012 about verification and validation of examination procedure]] 
-  - Explain measurement uncertainty and its requirements in ISO 15189-2012 +  - [[Explain measurement uncertainty and its requirements in ISO 15189-2012]] 
-  - Requirements in ISO 15189-2012 about documentation of examination procedures +  - [[Requirements in ISO 15189-2012 about documentation of examination procedures]] 
-  - Report content requirements in ISO 15189-2012 +  - [[Report content requirements in ISO 15189-2012]] 
-  - Requirements in ISO 15189-2012 about release of reports +  - [[Requirements in ISO 15189-2012 about release of reports]] 
-  - Information system management requirements in ISO 15189-2012 +  - [[Information system management requirements in ISO 15189-2012]] 
-  - Describe detailed process map of blood sample centrifugation. Identify risks involved in the process and possible steps to mitigate them. +  - [[Describe detailed process map of blood sample centrifugation. Identify risks involved in the process and possible steps to mitigate them.]] 
-  - nabl.pdf+  - [[nabl.pdf]]
  
 ====Medical Education==== ====Medical Education====
-  - Microteaching +  - [[Microteaching]] 
-  - OSPE and OSCE +  - [[OSPE and OSCE]] 
-  - Teaching methods for large group +  - [[Teaching methods for large group]] 
-  - Teaching methods for small group +  - [[Teaching methods for small group]] 
-  - Problem based learning +  - [[Problem based learning]] 
-  - Teaching aids +  - [[Teaching aids]] 
-  - Characteristics of good poster presentation +  - [[Characteristics of good poster presentation]] 
-  - Characteristics of good slide presentation to 150 student class +  - [[Characteristics of good slide presentation to 150 student class]] 
-  - How to write good MCQ question paper+  - [[How to write good MCQ question paper]]
  
 =====Pharmacology (Biochemical Mechanism of Action of Drugs) and Microbiology===== =====Pharmacology (Biochemical Mechanism of Action of Drugs) and Microbiology=====
-  - statin +  - [[statin]] 
-  - fibrate +  - [[fibrate]] 
-  - Niacin +  - [[Niacin]] 
-  - cholestyramin +  - [[cholestyramin]] 
-  - ezetimibe +  - [[ezetimibe]] 
-  - penicilline +  - [[penicilline]] 
-  - quinolone +  - [[quinolone]] 
-  - folate antagonists +  - [[folate antagonists]] 
-  - sulphonamide +  - [[sulphonamide]] 
-  - neuraminidase inhibitors +  - [[neuraminidase inhibitors]] 
-  - protease inhibitors +  - [[protease inhibitors]] 
-  - M protein inhibitor- amantidine +  - [[M protein inhibitor- amantidine]] 
-  - Reverse trascriptase inhibitors +  - [[Reverse trascriptase inhibitors]] 
-  - integrase inhibitors +  - [[integrase inhibitors]] 
-  - anti cancer drugs mechanism +  - [[anti cancer drugs mechanism]] 
-  - H1N1 +  - [[H1N1]] 
-  - HIV+  - [[HIV]]
  
 =====Immunology===== =====Immunology=====
-  - Immunoglobulin +  - [[Immunoglobulin]] 
-  - Complement +  - [[Complement]] 
-  - B cell Receptor +  - [[B cell Receptor]] 
-  - T Cell receptors +  - [[T Cell receptors]] 
-  - MHC +  - [[MHC]] 
-  - Immune diversityAllelic exclusion, DNA rearrangement in B and T cell, Junctional diversity, Somatic hypermutation, Isotype switching +  - [[Immune diversityAllelic exclusion, DNA rearrangement in B and T cell, Junctional diversity, Somatic hypermutation, Isotype switching]] 
-  - Extracelluar and intracellular antigen presentation +  - [[Extracelluar and intracellular antigen presentation]] 
-  - T Cell activation +  - [[T Cell activation]] 
-  - B Cell activation +  - [[B Cell activation]] 
-  - T cell and B cell effector functions +  - [[T cell and B cell effector functions]] 
-  - ADA, Chronic granulomatous disease, Ataxia Telegactesia +  - [[ADA, Chronic granulomatous disease, Ataxia Telegactesia]] 
-  - Autoimmunity +  - [[Autoimmunity]] 
-  * Self tolerance +  * [[Self tolerance]] 
-  * Central +  * [[Central]] 
-  * Peripheral +  * [[Peripheral]] 
-  * Loss of self tolerance +  * [[Loss of self tolerance]] 
-  * structural molecular mimicry +  * [[structural molecular mimicr]] 
-  * sequestration +  * [[Neoantigen]] 
-  * Neoantigen +  * [[Epitope spreading]]
-  * Epitope spreading+
  
 =====Clinical Chemistry===== =====Clinical Chemistry=====
-  - Ethical issues in clinical chemistry +  - [[Ethical issues in clinical chemistry]] 
-  - Process of introducing new laboratory method in routine use +  - [[Process of introducing new laboratory method in routine use]] 
-  - Repeatability, reproducibility, intermediate precision and interlaboratory precision +  - [[Repeatability, reproducibility, intermediate precision and interlaboratory precision]] 
-  - Measurement of within run precision using 20 sets of within-batch-duplicate measurement +  - [[Measurement of within run precision using 20 sets of within-batch-duplicate measurement]] 
-  - Precision profile of an examination at different analyte concentration +  - [[Precision profile of an examination at different analyte concentration]] 
-  - Evaluation of the Linearity of Quantitative Measurement Procedures CLSI EP 06-A +  - [[Evaluation of the Linearity of Quantitative Measurement Procedures CLSI EP 06-A]] 
-  - LoB,LoD,LoQ and LoL +  - [[LoB,LoD,LoQ and LoL]] 
-  - Procedures for setting analytical goals for clinical chemistry examinations +  - [[Procedures for setting analytical goals for clinical chemistry examinations]] 
-  - Bland Altman plot for comparison between two methods +  - [[Bland Altman plot for comparison between two methods]] 
-  - Absolute and relative Bland Altman plot for comparison between two methods +  - [[Absolute and relative Bland Altman plot for comparison between two methods]] 
-  - Regression analysis +  - [[Regression analysis]] 
-  - Concept of significant digits in clinical chemistry +  - [[Concept of significant digits in clinical chemistry]] 
-  - Traceability and measurement uncertainty +  - [[Traceability and measurement uncertainty]] 
-  - Sensitivity and specificity of diagnostic test and ROC curve +  - [[Sensitivity and specificity of diagnostic test and ROC curve]] 
-  - Types of clinical questions addressed in laboratory medicine with examples +  - [[Types of clinical questions addressed in laboratory medicine with examples]] 
-  - Hierarchy of evidences for decision making about appropriateness of a laboratory examination +  - [[Hierarchy of evidences for decision making about appropriateness of a laboratory examination]] 
-  - Standards for reporting diagnostic accuracy (STARD) used for evaluating evidence published for accuracy of laboratory test +  - [[Standards for reporting diagnostic accuracy (STARD) used for evaluating evidence published for accuracy of laboratory test]] 
-  - Critical appraisal and systemic review of diagnostic tests +  - [[Critical appraisal and systemic review of diagnostic tests]] 
-  - Economic evaluation of diagnostic tests +  - [[Economic evaluation of diagnostic tests]] 
-  - Different meanings of “Normal Value” and difference from “Reference value” and “Clinical decision limits” +  - [[Different meanings of “Normal Value” and difference from “Reference value” and “Clinical decision limits”]] 
-  - Conditions to compare patient results with reference values +  - [[Conditions to compare patient results with reference values]] 
-  - Strategies for selecting reference individuals for determining reference values of a diagnostic test +  - [[Strategies for selecting reference individuals for determining reference values of a diagnostic test]] 
-  - Parametric and nonparametric methods for determining reference values +  - [[Parametric and nonparametric methods for determining reference values]] 
-  - Univariate, multiple univariate and multivariate reference values +  - [[Univariate, multiple univariate and multivariate reference values]] 
-  - Subject based reference values +  - [[Subject based reference values]] 
-  - Circadian rhythm as preanalytical variable +  - [[Circadian rhythm as preanalytical variable]] 
-  - Diet and alcohol as preanalytical variable +  - [[Diet and alcohol as preanalytical variable]] 
-  - Noncontrollable preanalytical variable +  - [[Noncontrollable preanalytical variable]] 
-  - Biological variability of clinical chemistry examinations +  - [[Biological variability of clinical chemistry examinations]] 
-  - Recommended order of draw, stopper color, content and inversions +  - [[Recommended order of draw, stopper color, content and inversions]] 
-  - Types of vacuum tubes for collection of blood for serum +  - [[Types of vacuum tubes for collection of blood for serum]] 
-  - Newer advances in vacuum tubes technology for patient and phlebotomist safety +  - [[Newer advances in vacuum tubes technology for patient and phlebotomist safety]] 
-  - Skin puncture for sample collection +  - [[Skin puncture for sample collection]] 
-  - Arterial puncture for sample collection +  - [[Arterial puncture for sample collection]] 
-  - Various anticoagulents and preservatives in blood +  - [[Various anticoagulents and preservatives in blood]] 
-  - Collection of urine specimen +  - [[Collection of urine specimen]] 
-  - Cost of Quality with reference to clinical laboratory +  - [[Cost of Quality with reference to clinical laboratory]] 
-  - Concept of six sigma and measurement of sigma in a clinical chemistry laboratory +  - [[Concept of six sigma and measurement of sigma in a clinical chemistry laboratory]] 
-  - Calibrator traceability +  - [[Calibrator traceability]] 
-  - LJ Chart for quality control +  - [[LJ Chart for quality control]] 
-  - Westgard rules for interpretation of QC results +  - [[Westgard rules for interpretation of QC results]] 
-  - Control of quality using patient data from single and multiple patients +  - [[Control of quality using patient data from single and multiple patients]] 
-  - Desirable characteristics of EQA program for clinical chemistry +  - [[Desirable characteristics of EQA program for clinical chemistry]] 
-  - Explain Trueness, accuracy and precision with examples +  - [[Explain Trueness, accuracy and precision with examples]] 
-  - Explain repeatability and reproducibility with examples +  - [[Explain repeatability and reproducibility with examples]] 
-  - mole, molarity, molality and normality +  - [[mole, molarity, molality and normality]] 
-  - Concentration quantities and units in clinical biochemistry +  - [[Concentration quantities and units in clinical biochemistry]] 
-  - SI units in clinical biochemistry +  - [[SI units in clinical biochemistry]] 
-  - Standardized reporting of test results +  - [[Standardized reporting of test results]] 
-  - Reagent grade water – CLSI specifications and preparation/instrumentation +  - [[Reagent grade water – CLSI specifications and preparation/instrumentation]] 
-  - Reference materials, Reference methods and Reference laboratories +  - [[Reference materials, Reference methods and Reference laboratories]] 
-  - Measurement of volume in clinical chemistry +  - [[Measurement of volume in clinical chemistry]] 
-  - Micropipette/Pipette/ Volumetric flask calibration +  - [[Micropipette/Pipette/ Volumetric flask calibration]] 
-  - Types, operating principles, calibration, care and maintenance of centrifuges +  - [[Types, operating principles, calibration, care and maintenance of centrifuges]] 
-  - Buffers in clinical chemistry reagents – principles, preparation and uses +  - [[Buffers in clinical chemistry reagents – principles, preparation and uses]] 
-  - Ethical issues in clinical chemistry +  - [[Ethical issues in clinical chemistry]] 
-  - Hazards in clinical laboratory +  - [[Hazards in clinical laboratory]] 
-  - Classification of fires and fire extinguisher requirements +  - [[Color coding, order of draw, mixing recommendations of vacuum tubes for sample collection]] 
-  - Color coding, order of draw, mixing recommendations of vacuum tubes for sample collection +  - [[Causes and prevention of error and hazards in sample collection]] 
-  - Causes and prevention of error and hazards in sample collection +  - [[Beer's law, relationship between Transmittance and Absorbance and its application in clinical chemistry.]] 
-  - Beer's law, relationship between Transmittance and Absorbance and its application in clinical chemistry. +  - [[Explain concept and application of Molar Absorptivity giving suitable examples.]] 
-  - Explain concept and application of Molar Absorptivity giving suitable examples. +  - [[Draw diagram of a spectrophotometer. How double-beam-in-time spectrophotometer differ from double-beam-in-space spectrophotometer]] 
-  - Draw diagram of a spectrophotometer. How double-beam-in-time spectrophotometer differ from double-beam-in-space spectrophotometer +  - [[Spectral isolation in optical analytical equipments]] 
-  - Light sources in analytical equipments +  - [[Wavelengh accuracy, spectral band width, stray light and photometric accuracy of optical analytical equipments]] 
-  - Spectral isolation in optical analytical equipments +  - [[Principle, instrumentation and use of atomic absorption spectrometry in clinical chemistry]] 
-  - Wavelengh accuracy, spectral band width, stray light and photometric accuracy of optical analytical equipments +  - [[Zeeman correction in atomic absorption spectrometry]] 
-  - Principle, instrumentation and use of atomic absorption spectrometry in clinical chemistry +  - [[Principle of flurometry and fluroscence polarization]] 
-  - Zeeman correction in atomic absorption spectrometry +  - [[Components of flurometric equipment]] 
-  - Principle of flurometry and fluroscence polarization +  - [[Principles of Luminecence, bioluminecence, chemiluminecence, enhanced chemileuminecence and electrochemileuminicence]] 
-  - Components of flurometric equipment +  - [[Principle and instrumentation of nephelometry and turbidimetry]] 
-  - Principles of Luminecence, bioluminecence, chemiluminecence, enhanced chemileuminecence and electrochemileuminicence +  - [[Potentiometry using Ion selective electrodes for H+, Na+, K+ and Cl-]] 
-  - Principle and instrumentation of nephelometry and turbidimetry +  - [[Potentiometry electrodes for pCO2]] 
-  - Potentiometry using Ion selective electrodes for H+, Na+, K+ and Cl- +  - [[Amperometric electrode for pO2]] 
-  - Potentiometry electrodes for pCO2 +  - [[Amperometric O2 based and H2O2 based glucose electrodes]] 
-  - Amperometric electrode for pO2 +  - [[Potentiometric enzyme electrode for blood urea]] 
-  - Amperometric O2 based and H2O2 based glucose electrodes +  - [[Biosensors – enzyme based and affinity based]] 
-  - Potentiometric enzyme electrode for blood urea +  - [[Affinity sensors for specific protein and DNA detection]] 
-  - Biosensors – enzyme based and affinity based +  - [[Electrophoresis support media]] 
-  - Affinity sensors for specific protein and DNA detection +  - [[Isoelectric focusing]] 
-  - Electrophoresis support media +  - [[Principle of SDS PAGE]] 
-  - Isoelectric focusing +  - [[Troubleshooting SDS PAGE]] 
-  - Principle of SDS PAGE +  - [[Principle, instrumentation and uses of capillary electrophoresis]] 
-  - Troubleshooting SDS PAGE +  - [[Microchip electrophoresis]] 
-  - Principle, instrumentation and uses of capillary electrophoresis +  - [[Separation mechanisms used in chromatography]] 
-  - Microchip electrophoresis +  - [[Size exclusion chromatography]] 
-  - Separation mechanisms used in chromatography +  - [[Affinity chromatography]] 
-  - Size exclusion chromatography +  - [[Explain chromatographic resolution and efficiency]] 
-  - Affinity chromatography +  - [[Instrumentation of HPLC]] 
-  - Explain chromatographic resolution and efficiency +  - [[HPLC sample injector]] 
-  - Instrumentation of HPLC +  - [[HPLC columns]] 
-  - HPLC sample injector +  - [[HPLC detectors]] 
-  - HPLC columns +  - [[Instrumentation of Gas Chromatography]] 
-  - HPLC detectors +  - [[GC detectors]] 
-  - Instrumentation of Gas Chromatography +  - [[Principle of electron and chemical ionization in mass spectrometer]] 
-  - GC detectors +  - [[Electrospray Ionization for mass spectrometry]] 
-  - Principle of electron and chemical ionization in mass spectrometer +  - [[MALDI mass spectrometry]] 
-  - Electrospray Ionization for mass spectrometry +  - [[Principles of various mass analysers for mass spectrometry]] 
-  - MALDI mass spectrometry +  - [[Quadruple mass analysers]] 
-  - Principles of various mass analysers for mass spectrometry +  - [[Magnetic sector mass analysers]] 
-  - Quadruple mass analysers +  - [[TOF mass analysers]] 
-  - Magnetic sector mass analysers +  - [[Quadrupole and linear ion trap mass analysers]] 
-  - TOF mass analysers +  - [[Tandom mass spectrometry]] 
-  - Quadrupole and linear ion trap mass analysers +  - [[Clinical applications of mass spectrometer]] 
-  - Tandom mass spectrometry +  - [[Define isoenzymes. Explain genetic origin of isoenzymes. Enlist non-genetic modifications of enzymes resulting in isoforms.]] 
-  - Clinical applications of mass spectrometer +  - [[Measurement of enzymes by reaction rates]] 
-  - Define isoenzymes. Explain genetic origin of isoenzymes. Enlist non-genetic modifications of enzymes resulting in isoforms. +  - [[Strategy for detection of above-linearity range ALT in automated chemistry analysers]] 
-  - Measurement of enzymes by reaction rates +  - [[Traceability of enzyme measurement]] 
-  - Strategy for detection of above-linearity range ALT in automated chemistry analysers +  - [[Enzymes as analytical reagents]] 
-  - Traceability of enzyme measurement +  - [[Monoclonal antibody productions]] 
-  - Enzymes as analytical reagents +  - [[Labeled immunochemical assays]] 
-  - Monoclonal antibody productions +  - [[Competitive vs. noncompetitive immunoassay]] 
-  - Labeled immunochemical assays +  - [[Labels used for nonisotopic immunoassay and their detection limits]] 
-  - Competitive vs. noncompetitive immunoassay +  - [[Heterogenous vs. homogenous immunoassay]] 
-  - Labels used for nonisotopic immunoassay and their detection limits +  - [[CEDIA and EMIT]] 
-  - Heterogenous vs. homogenous immunoassay +  - [[Homogenous polarization fluroimmunoassay]] 
-  - CEDIA and EMIT +  - [[Principle of PCR]] 
-  - Homogenous polarization fluroimmunoassay +  - [[PCR optimization and primer design]] 
-  - Principle of PCR +  - [[PCR contamination control]] 
-  - PCR optimization and primer design +  - [[Hot start PCR]] 
-  - PCR contamination control +  - [[Asymmetric PCR]] 
-  - Hot start PCR +  - [[Allele specific PCR]] 
-  - Asymmetric PCR +  - [[Single molecule PCR]] 
-  - Allele specific PCR +  - [[Isothermic PCR amplification based on transcription]] 
-  - Single molecule PCR +  - [[PCR application detection techniques]] 
-  - Isothermic PCR amplification based on transcription +  - [[PCR amplicon discrimination techniques]] 
-  - PCR application detection techniques +  - [[PCR-RFLP]] 
-  - PCR amplicon discrimination techniques +  - [[Single stranded conformation polymorphism for discrimination of PCR products]] 
-  - PCR-RFLP +  - [[Denaturing gradient and temperature gradient electrophoresis for discrimination of PCR products]] 
-  - Single stranded conformation polymorphism for discrimination of PCR products +  - [[Dideoxy terminal sequencing of DNA principle and automated sequencing]] 
-  - Denaturing gradient and temperature gradient electrophoresis for discrimination of PCR products +  - [[Emulsion PCR]] 
-  - Dideoxy terminal sequencing of DNA principle and automated sequencing +  - [[Bridge amplification]] 
-  - Emulsion PCR +  - [[Absorbance melting curve of double helical nucleic acid]] 
-  - Bridge amplification +  - [[Dot-blot hybridization assay]] 
-  - Absorbance melting curve of double helical nucleic acid +  - [[Two color DNA microarray]] 
-  - Dot-blot hybridization assay +  - [[DNA copy number variation assay]] 
-  - Two color DNA microarray +  - [[Single copy visualization assay]] 
-  - DNA copy number variation assay +  - [[real time PCR with dsDNA binding dyes]] 
-  - Single copy visualization assay +  - [[Real time monitoring of PCR and melting analysis]] 
-  - real time PCR with dsDNA binding dyes +  - [[Detection, quantification and identification of amplicon in real time PCR]] 
-  - Real time monitoring of PCR and melting analysis +  - [[Common probes and dyes for realtime PCR]] 
-  - Detection, quantification and identification of amplicon in real time PCR +  - [[Microchip electrophoresis device]] 
-  - Common probes and dyes for realtime PCR +  - [[Automation in sample identification and data collection]] 
-  - Microchip electrophoresis device +  - [[Automation in sample transporters]] 
-  - Automation in sample identification and data collection +  - [[Describe components of a automated discrete analyser.]] 
-  - Automation in sample transporters +  - [[Use of barcoding in clinical laboratory]] 
-  - Describe components of a automated discrete analyser. +  - [[Components of Integrated automation system in clinical laboratory]] 
-  - Use of barcoding in clinical laboratory +  - [[Advantages and disadvantages of POCT]] 
-  - Components of Integrated automation system in clinical laboratory +  - [[Ideal requirements of POCT]] 
-  - Advantages and disadvantages of POCT +  - [[Classification of POCT devices]] 
-  - Ideal requirements of POCT +  - [[Principle of electrochemical glucose strip used in glucometers]] 
-  - Classification of POCT devices +  - [[Principle of lateral flow immunoassay]] 
-  - Principle of electrochemical glucose strip used in glucometers +  - [[Principles of HbA1C POCT instruments]] 
-  - Principle of lateral flow immunoassay +  - [[Assessing need for POCT service]] 
-  - Principles of HbA1C POCT instruments +  - [[**Principles, advantages,disadvantages, clinical interpretation** of various methods for measurement of ALT, AST, Amylase, LDH, CKMB, Psudocholinesterase, ALP, Lipase, total protein, albumin, creatinine, urea, uric acid, Glucose,Cholesterol, TG, HDL, LDL, iron, TIBC HbA1C, Bilirubin, TSH, T4, Free T4, Other hormones and tumor markers]] 
-  - Assessing need for POCT service +  - [[Describe genetics, clinical significance,methods for determinations, reference intervals for serum alkaline phosphatase]] 
-  - **Principles, advantages,disadvantages, clinical interpretation** of various methods for measurement of ALT, AST, Amylase, LDH, CKMB, Psudocholinesterase, ALP, Lipase, total protein, albumin, creatinine, urea, uric acid, Glucose,Cholesterol, TG, HDL, LDL, iron, TIBC HbA1C, Bilirubin, TSH, T4, Free T4, Other hormones and tumor markers]] +  - [[Current applications of tumor markers and their limitations]] 
-  - Describe genetics, clinical significance,methods for determinations, reference intervals for serum alkaline phosphatase +  - [[Current recommendations on use of tumor markers]] 
-  - Current applications of tumor markers and their limitations +  - [[Enzymes as tumor markers]] 
-  - Current recommendations on use of tumor markers +  - [[Screening for urine microalbuminuria in diabetes mellitus]] 
-  - Enzymes as tumor markers +  - [[Describe formation of creatinine in body Describe salient features of chemical and enzymatic methods for serum creatinine measurement. Give account of quality issues in creatinine measurement. List advantages and disadvantages of markers of GFR. Explain use of IDMS traceable MDRD equation for estimating GFR from serum creatinine.]] 
-  - Screening for urine microalbuminuria in diabetes mellitus +  - [[DM diagnostic guideline]] 
-  - Describe formation of creatinine in body Describe salient features of chemical and enzymatic methods for serum creatinine measurement. Give account of quality issues in creatinine measurement. List advantages and disadvantages of markers of GFR. Explain use of IDMS traceable MDRD equation for estimating GFR from serum creatinine. +  - [[ATP IV Hypercholesterolemia diagnostic guidline]] 
-  - DM diagnostic guideline +  - [[Cholesterol reference material, method and laboratories]] 
-  - ATP IV Hypercholesterolemia diagnostic guidline +  - [[beta thalassemia – genetics, pathogenesis, diagnosis]] 
-  - Cholesterol reference material, method and laboratories +  - [[Explain different types of isoenzymes and isoforms of Creatine Kinase in humans. Describe principle of measurement of CK-MB by catalytic method and mass method. Why the catalytic method generally contain N-acetyl cysteine, AMP and diadenosine-pentaphosphate]]
-  - beta thalassemia – genetics, pathogenesis, diagnosis +
-  - Explain different types of isoenzymes and isoforms of Creatine Kinase in humans. Describe principle of measurement of CK-MB by catalytic method and mass method. Why the catalytic method generally contain N-acetyl cysteine, AMP and diadenosine-pentaphosphate+