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| deficiancy_of_lipoprotein_lipase_results_in_hypertriglyceridemia [2025/02/07 05:54] – created admin | deficiancy_of_lipoprotein_lipase_results_in_hypertriglyceridemia [2025/02/10 04:31] (current) – admin | ||
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| - | The enzyme lipoprotein lipase (LpL) is located at | + | **Deficiancy of Lipoprotein lipase results in hypertriglyceridemia** |
| - | the endothelial layer of capillaries of adipose tissue, | + | |
| - | muscles and heart; but not in liver. Apo C-II present | + | * The enzyme lipoprotein lipase (LpL) is located at the endothelial layer of capillaries of adipose tissue, muscles and heart; but not in liver. |
| - | in the chylomicrons activates the LpL .The | + | * Apo C-II present in the chylomicrons activates the LpL . |
| - | LpL hydrolyzes triglycerides present in chylomicrons | + | * The LpL hydrolyzes triglycerides present in chylomicrons into fatty acids and glycerol. |
| - | into fatty acids and glycerol. Muscle or adipose tissue | + | * Muscle or adipose tissue cells take up the liberated fatty acids. |
| - | cells take up the liberated fatty acids | + | |
| - | Hence deficiency of lipoprotein lipase leads to high triglycerides levels in blood | + | |