**Insulin is use to prevent hyperkalaemia**

Hyperkalaemia is increase in Plasma potassium level above 5.5 mmole/litre

CAUSES:

1) Impaired Excretion :
  - Acute kidney injury
  - Cirrhosis
  - Drug intake [NSAIDs]

2) Transcellular shifts :
  - Acidosis
  - Hyperglycemia


**TREATMENT**

  * Insulin indirectly stimulates Na-K ATPase Pump. 
  * Which Causes 3 Na out and 2 K inside the cell. 
  * So Potassium enters the cell and its concentration decrease in the blood stream (Mainly in skeletal muscle cell)

IMPORTANT NOTE :
Insulin is given in conjugation with glucose to prevent hypoglycaemia.
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**MECHANISM**
  - Insulin Activate Na-Glucose transporter
  - Na and Glucose enter in the cell
  - Na-K pump Action : 3 Na+ OUT and 2 K+ IN
  - K+ concentration in plasma decreases
  - Hyperkalemia Prevented