**Hyaluronidase is called as spreading factor**

  * Hyaluronic acid is a key component of connective tissue that maintain cell structure and viscosity
  * Hyaluronidase breaks down hyaluronic acid
  * This allows fluids and toxins to spread through the tissue and it helps bacteria to penetrate host tissue 
  * This enzyme is also important in      
                  -  Tissue Permiability 
                  -  bacterial invasion  
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