Show pageOld revisionsBacklinksBack to top This page is read only. You can view the source, but not change it. Ask your administrator if you think this is wrong. **IODINE DEFICIENCY IN DIET LEADS TO GOITRE** * During the low levels of T3 and T4 the hormones TRH and TSH are released. * The TSH binds to TSH receptor on basal membrane of Follicular cell and results in the formation of raw materials for thyroid hormone synthesis. * The raw materials can be converted to T3 and T4 only when reaction with iodine is done. * But as the iodine is deficit, so this substances will get accumulated in the colloid . * The T3 and T4 levels will be continuously low in blood which will result in continuous synthesis of raw materials and their accumulation. * Thus, iodine deficiency in diet leads to goitre {{ :img_4099.jpeg?400 |}}