Differences
This shows you the differences between two versions of the page.
| Both sides previous revision Previous revision Next revision | Previous revision | ||
| niacin_deficiency_alone_can_not_cause_pellagra [2025/02/10 04:04] – admin | niacin_deficiency_alone_can_not_cause_pellagra [2025/02/11 05:31] (current) – admin | ||
|---|---|---|---|
| Line 6: | Line 6: | ||
| - Diets low in both niacin and tryptophan, such as those heavily reliant on corn without proper preparation, | - Diets low in both niacin and tryptophan, such as those heavily reliant on corn without proper preparation, | ||
| * Thus, while niacin deficiency is a key factor, other nutritional and metabolic issues also play a role. | * Thus, while niacin deficiency is a key factor, other nutritional and metabolic issues also play a role. | ||
| + | |||
| + | |||
| + | ---- | ||
| + | |||
| + | * Niacin deficiency alone cannot cause pellagra because the body can also synthesize niacin from the amino acid tryptophan. | ||
| + | * even if dietary niacin is low, adequate tryptophan intake can prevent pellagra. | ||
| + | * therefore, a deficiency in both niacin and tryptophan is necessary for the development of the disease. | ||
| + | * Eg, Diets high in corn, which is low in both niacin and readily available tryptophan, are often associated with pellagra because the body cannot efficiently convert the bound niacin in corn. | ||
| + | |||
| + | {{ : | ||