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molecular_biology [2023/10/29 16:21] – created quality_managermolecular_biology [2025/01/08 16:15] (current) – external edit 127.0.0.1
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-1. Post-translational modifications in collagen+1. Post-translational modifications in collagen/Order and location of various post-translational processing of collagen  
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 +2. DNA packaging in metaphase chromosomes 
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 +3. Possible roles of modified histones 
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 +4. Major features of human mitochondrial DNA 
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 +5. Viral integration and transposons in human genome 
 + 
 +6. Structure, function and inhibitors of DNA topoisomerases 
 + 
 +7. DNA damage – causes, types, repair pathways and repair fedality 
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 +8. Double stranded break repair mechanisms 
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 +9. Transcription cycle 
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 +10. Transcription control regions for eukaryotic genes 
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 +11. Post-trancriptional modification of primary transcript 
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 +12. Mechanism of intron removal and alternative splicing 
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 +13. Alternative promotor utilization 
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 +14. Biogenesis and function of miRNA 
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 +15. Degeneracy of genetic code, concept and mechanism of wobbling phenomenon 
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 +16. Properties of genetic code 
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 +17. Point mutations and frame shift mutations 
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 +18. Circularization of mRNA during translation 
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 +19. Role of methyl-GTP cap and poly-A tail in translation 
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 +20. Antibiotics inhibiting protein synthesis 
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 +21. cis and trans epigenetic signals 
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 +22. Propagation of epigenetic signal after DNA replication 
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 +23. Properties of enhancers 
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 +24. DNA motifs 
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 +25. Various ways of gene regulation 
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 +26. Regulation of mRNA stability 
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 +27. Restriction - Enzymes used in recombinant DNA research 
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 +28. structure pf plasmid pBR322 and its use in recombinant DNA technology 
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 +29. genomic and cDNA library 
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 +30. DNA sequencing by Sanger'
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 +31. Transgenic animals and knockout animals 
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 +32. Hypoxia induced molecular events leading to altered gene expression